pgp - publications
Potent and selective tariquidar bioisosters as potential PET radiotracers for imaging P-gp.
Bioorg Med Chem Lett. 2013 Jan 5;
Authors: Contino M, Zinzi L, Perrone MG, Leopoldo M, Berardi F, Perrone R, Colabufo NA
Compounds 8a-d have been designed as bioisosters of tariquidar for imaging P-gp expression and density by PET. The results displayed that compounds 8b and 8d could be considered potential P-gp/BCRP ligands suitable as (11)C and (18)F radiotracers, respectively.
PMID: 23374872 [PubMed - as supplied by publisher]